Ampyra is used to improve walking in patients with multiple sclerosis (MS). Dalfampridine produced an increase in walking speed in clinical trials. Exactly how it works is not known. It is thought to increase nerve function.

IMPORTANT SAFETY INFORMATION

Talk to your doctor about AMPYRA to learn if it is safe for you. Do not take it if you’ve ever had a seizure or if you have certain types of kidney problems as this may increase your risk of seizure. Tell your doctor if you have kidney problems.

Never take more than one tablet of AMPYRA twice a day (about 12 hours apart). Don’t take more than 2 tablets in a 24-hour period because it may increase the risk of seizures. If you miss a dose of AMYPRA don’t make up the missed dose.

Do not take AMPYRA together with other aminopyridine medications, including compounded 4- aminopyridine (sometimes called 4-AP, fampridine).

AMPYRA may cause serious side effects, including kidney or bladder infections. The most common side effects are urinary tract infection, trouble sleeping (insomnia), dizziness, headache, nausea, weakness, back pain, and problems with balance. Tell your doctor if you have any of these side effects that bother you or do not go away.

Important information about Ampyra

You should not use Ampyra if you are allergic to dalfampridine, or if you have moderate to severe kidney disease, if you have ever had a seizure (convulsions), or if you are also taking another multiple sclerosis drug called Fampridine.

If you have mild kidney disease, you may need a dose adjustment or special tests.

Do not take more than 2 Ampyra tablets in a 24-hour period. Do not use a tablet that has been broken or crushed. A broken tablet can release too much of the drug at one time. This can increase your risk of having a seizure. Stop taking Ampyra and call your doctor at once if you a seizure, pain or burning when you urinate, problems with your balance, numbness or tingly feeling, or a relapse of your MS symptoms.





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