Carre Otis was born in San Francisco, and raised in Marin County, California along with her older sister Chrisse and her younger brother Jordan. She attended Marin Academy in San Rafael, California and the John Woolman School in Nevada City, California.

Otis began modeling at age 16. Discovered in San Francisco, she was initially signed to Elite Model Management by John Casablancas. She first achieved fame while working for Elite in Paris, when she appeared on the cover of French Elle in April 1986. Over the next several years, she appeared on covers in the American and foreign editions of Vogue, Harper's Bazaar, Cosmopolitan, Allure, Mirabella, and Marie Claire.

Otis appeared in ads for Guess jeans (1988), Calvin Klein jeans ("biker chick" look, 1991), appeared in the 1996 Pirelli calendar, and also posed for the Sports Illustrated swimsuit edition (2000). Otis was also featured in 1990 and 2000 issues of Playboy magazine.

Otis started dating Mickey Rourke not long after the release of Wild Orchid. The couple married in 1992, and had one of the most celebrated and stormy celebrity marriages of the 1990s. In 1994, Rourke was arrested for spousal abuse, but the charges were later dropped. Otis battled anorexia and drug dependency, addictions that had tormented her since her adolescence. With Rourke's help, Otis was able to get clean from heroin in 1994, but her struggles with other substances continued until 1996. In 2001, Otis said that she had mixed everything, including "alcohol, anti-depressants, uppers, downers and diet pills". She noted in that same interview that she and Rourke "had equally explosive personalities" (and she had) her own depression. We were both drama addicts." For several years before and during their marriage, Rourke refused to allow Otis to model, forcing her to turn down lucrative opportunities and threatening photographers and agents with whom she had worked. The couple eventually divorced in 1998.

She said, "I was constantly getting myself into horrific sexual encounters that you would classify as rape, and yet there wasn't a part of me that could scream, 'No!'
I was always in the wrong relationships, so I decided to see what would happen if I took that energy and focused it elsewhere. I live like a nun now.”

Hardly the only one speaking out on this matter Carré Otis is a former supermodel who survived anorexia, heroin/cocaine addiction, and repeated rapes. Prior to her 1999 heart seizure her drug addiction was getting steadily worse, she was surviving on green tea and small doses of vegetarian food, and she was easily persuaded into drugs and unsolicited sex because she couldn't say no to the people paying for her expensive lifestyle.



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