Annie Chapman eventually moved to Whitechapel, where in 1886 she was living with a man who made wire sieves; because of this she was often known as Annie "Sievey" or "Siffey". After she and her husband separated, she had received an allowance of 10 shillings a week from him, but at the end of 1886 the payments stopped abruptly. On inquiring why they had stopped, she found her husband had died of alcohol-related causes. The sieve-maker left her soon after, possibly due to the cessation of her income. One of her friends later testified that Chapman became very depressed after this and went downhill. Her friends called her "Dark Annie".
By 1888 Chapman was living in common lodging houses in Whitechapel, occasionally in the company of Edward "the Pensioner" Stanley, a bricklayer's labourer. She earned some income from crochet work, making antimacassars and selling flowers, supplemented by casual prostitution. An acquaintance described her as "very civil and industrious when sober", but noted "I have often seen her the worse for drink."
In the week before her death she was feeling ill after being bruised in a fight with Eliza Cooper, a fellow resident in Crossingham's lodging house at 35 Dorset Street, Spitalfields. The two were reportedly rivals for the affections of a local hawker called Harry, but Eliza claimed the fight was over a borrowed bar of soap that Annie had not returned.
Chapman may have been killed as late as 5:30 a.m., in the enclosed back yard of a house occupied by sixteen people, none of whom had seen or heard anything at the time of the murder. The passage through the house to the back-yard was not locked, as it was frequented by the residents at all hours of the day, and the front door was wide open when the body was discovered. Richardson said that he had often seen strangers, both men and women, in the passage of the house. Dr George Bagster Phillips, the police surgeon, described the body as he saw it at 6:30 a.m. in the back yard of the house at 29 Hanbury Street:
The left arm was placed across the left breast. The legs were drawn up, the feet resting on the ground, and the knees turned outwards. The face was swollen and turned on the right side. The tongue protruded between the front teeth, but not beyond the lips. The tongue was evidently much swollen. The front teeth were perfect as far as the first molar, top and bottom and very fine teeth they were. The body was terribly mutilated ... the stiffness of the limbs was not marked, but was evidently commencing. He noticed that the throat was dissevered deeply; that the incision through the skin were jagged and reached right round the neck ... On the wooden paling between the yard in question and the next, smears of blood, corresponding to where the head of the deceased lay, were to be seen. These were about 14 inches from the ground, and immediately above the part where the blood from the neck lay. ...
The instrument used at the throat and abdomen was the same. It must have been a very sharp knife with a thin narrow blade, and must have been at least 6 to 8 inches in length, probably longer. He should say that the injuries could not have been inflicted by a bayonet or a sword bayonet. They could have been done by such an instrument as a medical man used for post-mortem purposes, but the ordinary surgical cases might not contain such an instrument. Those used by the slaughtermen, well ground down, might have caused them. He thought the knives used by those in the leather trade would not be long enough in the blade. There were indications of anatomical knowledge ... he should say that the deceased had been dead at least two hours, and probably more, when he first saw her; but it was right to mention that it was a fairly cool morning, and that the body would be more apt to cool rapidly from its having lost a great quantity of blood. There was no evidence ... of a struggle having taken place. He was positive the deceased entered the yard alive ...
A handkerchief was round the throat of the deceased when he saw it early in the morning. He should say it was not tied on after the throat was cut.
Her throat was cut from left to right, and she had been disembowelled, with her intestines thrown out of her abdomen over each of her shoulders. The morgue examination revealed that part of her uterus was missing. Chapman's protruding tongue and swollen face led Dr Phillips to think that she may have been asphyxiated with the handkerchief around her neck before her throat was cut. As there was no blood trail leading to the yard, he was certain that she was killed where she was found. He concluded that she suffered from a long-standing lung disease, that the victim was sober at the time of death, and had not consumed alcoholic beverages for at least some hours before it. Phillips was of the opinion that the murderer must have possessed anatomical knowledge to have sliced out the reproductive organs in a single movement with a blade about 6–8 inches (15–20 cm) long. However, the idea that the murderer possessed surgical skill was dismissed by other experts. As her body was not examined extensively at the scene, it has also been suggested that the organ was removed by mortuary staff, who took advantage of bodies that had already been opened to extract organs that they could then sell as surgical specimens. In his summing up, Coroner Baxter raised the possibility that Chapman was murdered deliberately to obtain the uterus, on the basis that an American had made inquiries at a London medical school for the purchase of such organs. The Lancet rejected Baxter's suggestion scathingly, pointed out "certain improbabilities and absurdities", and said it was "a grave error of judgement". The British Medical Journal was similarly dismissive, and reported that the physician who requested the samples was a highly reputable doctor, unnamed, who had left the country 18 months before the murder. Baxter dropped the theory and never referred to it again. The Chicago Tribune claimed the American doctor was from Philadelphia, and author Philip Sugden later speculated that the man in question was the notorious Francis Tumblety.
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